Positive urine check may not be diabetic

"Familial renal diabetes," many are benign, patients typically have no complaints, nor can have serious consequences, the disease prognosis is good, usually do not require treatment.

But because a small number of renal diabetes, will be converted into real diabetes, renal glycosuria, to follow-up on. When I add these words to tell them, both of the following relief yeer will happily on the return journey.

In fact, this is similar to his father and misdiagnosis of example and not uncommon, especially at the grass-roots level countryside.

Here again, the diagnosis is based on the diabetes blood sugar instead of urine, the urine is not necessarily positive is diabetic, because in addition to diabetes, there are many other reasons, such as

1. after diabetes (also known as the "nourishing of diabetes"): diabetes occurs after feeding large quantities of sugar in the food or to absorb too fast, leading to a temporary rise in blood glucose concentration exceeds the threshold for renal glucose transient diabetes, but their fasting blood sugar and glucose tolerance test normal.

2, hunger of diabetes: chronic hunger people suddenly a meal, especially after consuming large amounts of sweets, tend to be positive urine.

This is because the hunger period, due to the low blood glucose, insulin B cells in half rest State. When suddenly a lot after eating, islet B cells couldn't adapt, insulin-producing relatively insufficient blood sugar rise and diabetes and temporary. In addition, hunger is increasing, growth hormone secretion also enables impaired glucose tolerance, this also causes the glucose and diabetes. Identification of recent attention asked diet, if necessary, to adequate food (250 grams per day), three days later repeated glucose tolerance test can identify.

3. stress diabetes: common in acute ischemic stroke, brain injury, skull fracture, brain tumors, narcotic, etc.

In these highly required in stressful situations, sometimes too high blood glucose will be temporary, with diabetes; with the stress State ends or anesthetics, will return to normal blood glucose, glucose into negative.

4, renal glycosuria: because of the renal tubules and absorption capacity reduced glucose (glomerular filtration rate and still working), renal glucose threshold decline, normal blood glucose and urine tested.

Renal diabetes is largely due to kidney damage near tubule, common

① pregnant women, minorities (10% ~ 15%) of women in late pregnancy may result in a transient renal glucose threshold is low and diabetes, its mechanism may be due to the extracellular fluid volume increase and inhibits the renal tubular reabsorption of glucose function, so that kidney decrease glucose threshold

② familial renal diabetes (also known as the "primary renal glycosuria" or "healthy diabetes"), this disease and heredity, and mostly autosomal, family members often have many sick patients except renal tubular reabsorption of hypothyroidism, other renal are OK, not associated with abnormal metabolism of fat, protein, good prognosis

③ chronic kidney diseases such as chronic nephritis, renal disease, and sometimes can be by renal tubular reabsorption of glucose and dysfunction appear diabetes

④ other rare genetic or acquired renal tubular disease, such as "Fanconi syndrome", can also be a diabetes, patients with positive except urine, the urine also contains a large number of amino acid and phosphate and carbonate crystallization, patients often have bone pain, pathological fracture, rickets and growth retardation.

Renal diabetes often and some related renal tubular defect, it features diabetes and not associated with hyperglycemia, patients regardless of fasting or after a meal, a urine specimen contains glucose, fasting glucose and glucose tolerance test are OK.

5. false sugar in urine (urine false-positive): determination of copper sulfate urine usually test is the use of sugar in the reductive color.

But there are many substances in urine with reductive, glucuronic acid, uric acid, vitamin C, or some with urinary excretion of the drug ruyi isoniazid, chloral hydrate, morphine, Digitalis, diuretics and other thiazide, when they increase in concentration in the urine, the urine can also be a false positive, called "pseudo diabetes." Clinical available through special glucose test, such as glucose oxidase test, and other urinary excretion with reductive substance identification of disease phase.

It can be seen, where the urine should be positive for diabetes related checks (such as "impaired glucose tolerance test"), to expressly diagnoses, must not be merely a urine results positive for diabetes on easily arrive at conclusions, otherwise, would lead to misdiagnosis, mistreatment, patients suffer undue losses and damage.

(Edit: internships, Lai-King)