Islet function is a good check list to see two

Once you have diabetes, know to diet, exercise, medications.

However, in various scientific blood glucose control measures, some people find diabetes blood sugar is still difficult to control. In fact, this situation in diabetic patients are not uncommon, mainly in conducting high-glycemic control while ignoring the islet function to protect this key point.

The islet is the only human insulin secretion, insulin function of organs, long-term stable sound to control blood sugar.

If the islet function decline, diabetics can only passively frequent dressing changes, eventually when various drugs effects are not satisfactory, you can only rely on insulin to control. Therefore long-term monitoring islet function, for all diabetes patients it is extremely important. Then, the islet function evaluation, which targets the most illustrative? most notably c-peptide and insulin antibodies.

C-peptide levels is to assess the islet function is an important tool, particularly for already using insulin therapy of patients is essential for more.

C-peptide is the containing 31 amino acids, peptides, with proposed insulin can promote glycogen synthesis and uptake of amino acids. As a result of c-peptide from insulin antibodies against interference, also without external insulin injection, so its concentration can assess the secretion of pancreatic islet cells. Normal human serum c-peptide 1.5 ± 0.23 ng/ml, 60 minutes after oral administration of glucose 4.4 ± 0.8 ng/ml, type 2 diabetes patients only rose to 2.3 ng/ml, and type 1 diabetes mellitus patients with c-peptide before dinner and after dinner are below normal.

Currently, clinically proven, high levels of insulin antibodies in patients with diabetes and retinopathy occurs earlier.

Because insulin antibody combination with insulin, on the islet cells produce immune injury and damage caused by insulin. At the same time, to generate large amounts of insulin antibody will lead to the patient is not sensitive to insulin, thus undermining the effectiveness of insulin preparations, the patient had to increase the dose of insulin, leading to a vicious cycle, this phenomenon is called "insulin resistance". Insulin resistance occurs in patients with serum insulin antibody binding capacity greater than nine units, rather than resistance to the following five units, most smaller than 0.1 units. If the diagnosis is not sensitive to the insulin or insulin resistance, the only effective solution is to use high-purity insulin.

Human islet cells once the damage will not be able to regenerate, so the various stages of diabetic people to pay attention to the protection of the islet function.

It is worth noting that the insulin in the pancreas function of protection plays an extremely important role, and if the blood glucose control, early application of insulin to control the illness.

(Edit: internships, Lai-King)