Friday, April 15, 2011

Treatment of Gout often fall into the "vicious circle".

Treatment of Gout often fall into the "vicious circle" often fall into the holmium Zi rank ︹ "/> Department of Nephrology, Zhongshan Hospital, Fudan University, deputy chief physician Zou Jianzhou Gout is a kind of blood uric acid increased and the joint characterized by recurrent painful swelling of the disease, the nature of .purine metabolism in vivo, can keep the plot on the joints caused by arthritis, leading to painful swelling of joints. Therefore, the key to prevention is to control gout uric acid levels. Unfortunately, we currently lack of awareness, clinical gout treatment .often occur during some "cycle." cycle 1: only in the acute treatment of acute exacerbation of the patient as a result of unbearable pain and often will go to the hospital, and once improved joint pain, the patient thinks .disease has been "good", and do not need to see the doctor, and does not require re-treatment. Analysis: In fact, gout treatment is divided into acute treatment and chronic maintenance phase of treatment, the key to prevention of chronic maintenance therapy, including dietary .conditioning, adequate exercise, joint protection, and uric acid lowering drugs when necessary, so that a certain level of uric acid control, to avoid another attack of gouty arthritis and so on. Therefore, even if joint pain improved, the patient still needs regular hospital follow-up. .cycle 2: increase the dose without increased serum uric acid is a key factor in a gout attack, so many patients that will rapidly reduce the level of serum uric acid, gout attacks can be avoided. For this reason, some patients without the drug dose increased, expectations of .serum uric acid levels can be reduced to lower in the short term. Analysis: Actually, this is often counterproductive. because when a higher level of blood uric acid rapidly reduced, on the one hand can make the already deposited in the joints and surrounding tissue insoluble urate .crystal drops off, and on the other hand can make the deposition of uric acid in the joint cavity, resulting in acute gouty arthritis. For this reason, doctors often require patients to slowly lower the blood uric acid levels. If necessary, patients can, under the guidance of doctors, the United .with uric acid lowering drugs and colchicine (or non-steroidal anti-inflammatory drugs) to avoid acute attack of gouty arthritis. circle 3: fear of side effects in clinical drug refusal, many patients that medication side effects, so do not want to .Long-term medication. some patients are using so-called "diet" therapy in an attempt to control through diet alone to achieve the purpose of lowering blood uric acid level. Analysis: 70% of the body of uric acid from 80% of the human body itself, and only .20% to 30% from food and other external factors. Therefore, for patients with high serum uric acid level, only using diet and other non-drug treatment, it is often difficult to reduce to the desired level of blood uric acid. At this point, need to be treated with drugs .. Of course, any drug has side effects, but uric acid lowering drugs, as long as properly used, side effects or small, patients do not have too much tension. In short, if patients insist on proper treatment, will be able to control the serum uric acid level, .to good control of gout attacks and avoid complications. and regular treatment can also prevent the occurrence of side effects. Related Links: serum uric acid control standards asymptomatic hyperuricemia patients, male serum uric acid should be controlled at 420 micromolar ./ l (7 mg / dl) below the control in 360 women micro mol / l (6 mg / dl) the following; repeated episodes of gout patients, serum uric acid should be controlled at lower levels, such as 300 micro mol / L ( .5 mg / dl) or less. text see "Family Health News" March 16, 2010 2 "Medical Guide".

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